Relationship between platelet-to-lymphocyte ratio and the presence and severity of coronary artery ectasia

OBJECTIVE The aim of this study was to investigate the relationship between platelet-to-lymphocyte ratio (PLR), an easily available inflammatory marker, and coronary artery ectasia (CAE). METHODS After applying the exclusion criteria, the retrospective study population consisted of 330 patients, including 110 patients with isolated CAE, 110 with obstructive coronary artery disease (CAD), and 110 with normal coronary artery angiograms (NCA). The severity of isolated CAE was determined according to the Markis classification. SPSS 22.0 statistical package program was used for data analysis. RESULTS PLR was significantly higher in patients with isolated CAE than in those with NCA and obstructive CAD [123 (113-156), 100 (86-138), and 110 (102-141), respectively]. Logistic regression analysis showed that PLR and C-reactive protein level were significantly correlated with the severity of isolated CAE. CONCLUSION To the best of our knowledge, this study showed for the first time that PLR was significantly associated with CAE.